By Tomris Coban
Consumer health products are becoming more important in our everday lives and the increasing use of these products has led Industry to want to have greater understanding of not only how well a new formulation works, but why it works. Our academic research group (KASNMR) have developed a strategic partnership with small R and D groups to answer niche questions on physiochemical interactions not previously explored by product development scientists. The use of heteronuclei 2D NMR techniques and Diffusometry, alongside classic homonuclear (1H) 2D NMR have demonstrated great potential in understanding how the addition, substitution and removal of excipients effects not only one property of formulations but can have holistic effects not previously understood. Linking reverse Heteronuclear STD, DOSY and heteronuclear qNMR results to one another has allowed for the implementation of the MICAH platform used at KASNMR for a complete suite of problem-solving experiments that can be catered to industrial chemists, product scientists or innovations scientists specific needs at different stages of new product development.