In the last decades, highly pure physical reference materials have played a crucial role in analytical and pharmaceutical chemistry. These highly valuable materials have been used for the structure verification and quantification of main compounds and excipients. The use of physical materials as references involves the purchase and the availability of the standard as well as additional sample preparation leading to longer measurement times. In MiliporeSigma (Merck KGAA), we want to keep shaping the future of analytical testing by building an online platform (ChemisTwin) that provides analytical solutions englobing different techniques. The first technique that the portal aimed at is Nuclear Magnetic Resonance (NMR) due to the reproducibility and simplicity of the technique when compared to other well-established techniques such as chromatography and mass spectrometry. NMR is one of the analytical techniques most used in organic chemistry and industry. ChemisTwin portal will contain an extensive database of electronic reference materials (eRM) acting as digital twins of the physical reference materials. These eRM are produced from physical certified reference materials (CRM) and the eRM is based on a digital package of datasets that defines a physical material. The production process of the eRM ensures the full traceability of the physical material. The use eRMs in the platform allows customers to perform the identity verification and content determination of their analytes of interest by uploading the raw data from the corresponding instrument. This solution allows the customer to automatically compare their sample with the eRM and provides a detailed report. This product provides our customers with a readily available, more sustainable, significantly less involved, and more error-proof solution.
